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Histamine and Endometriosis

Hista-what?

Hista-mine. It's the chemical your body produces from mast cells in your immune system that leads to allergies and swelling. It can be an issue for those with endometriosis. While histamine is important for stomach acid production, many functions in the central nervous system, and a key player in ovulation and sex hormone regulation; it can be troublesome for those with endometriosis.

Symptoms of histamine intolerance can include:

  • Food allergies and airborne allergies

  • Dizziness

  • Sneezing

  • Wheezing

  • Runny or congested nose

  • Red, itchy eyes

  • Rashes and hives

  • Racing heart

  • Chest tightness

  • Diarrhoea

  • Nausea

  • Irregular heart beat

  • Brain fog

  • Irritability

Endo flares and symptoms may be aggravated or made worse by high histamine foods since there may be an underlying issue with breaking it down. Going on a low histamine diet can make a big difference in many cases until the bodies overall functioning has improved. This relates to addressing gut health including dysbiosis and SIBO, improving the oestrogen/progesterone ratio, and replenishing nutrients that support histamine N-methyltransferase (HNMT) and diamine oxidase (DAO), the enzymes required to break down histamine. These include ensuring there is adequate methyl groups, B6 and vitamin C. Nutraceuticals are also key in regulation of mast cells and histamine levels, these include quercitin and bioflavonoids.


For a short period of time, eliminating histaminergic foods may be beneficial to reduce symptoms until the underlying issues are resolved.

Foods to focus on:

  • Almond or rice milk

  • Olive oil

  • Fresh cooked meat

  • Fresh fish (avoid shellfish)

  • Eggs (if tolerated)

  • Brown rice

  • Leafy greens excluding spinach

  • Hemp and chia seeds

  • Flaxseed meal

  • Vegetables (avoid tomatoes, eggplant and spinach)

  • Herbals teas

  • Most fruit (But no more than one or two pieces per day and avoid banana)


Foods to avoid:

  • Alcohol, particularly wine and cider

  • Chocolate

  • Avocado

  • Bananas

  • Sauerkraut

  • Kombucha

  • Anything fermented

  • Ham or bacon

  • Corned beef

  • Tinned fish

  • Soy sauce

  • Long cooked stews or bone broths

  • Vinegar products

  • Tomato

  • Eggplant

  • Spinach

  • Shellfish

Contrary to popular belief, there is no one-size-fits-all dietary approach with endometriosis and sometimes it takes a bit of trial and error to work out what is best for you.

If you are struggling to work out which foods to eat and which ones to ditch, feel free to reach out. I'd love to help

Bec xx






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